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<h3>Job Description</h3>
Job DescriptionSalary: 
About Aura:
 
Aura Biosciences is a clinical-stage biotechnology company focused on developing precision therapies for solid tumors that aim to preserve organ function. Our lead candidate, bel-sar (AU-011), is currently in late-stage development for primary choroidal melanoma and in early-stage development in other ocular oncology indications and bladder cancer. Aura Biosciences is headquartered in Boston, MA. Our mission is to grow as an innovative global oncology company that positively transforms the lives of patients.
For more information, visitaurabiosciences.com. Follow us on X (formerly Twitter) @AuraBiosciences and visit us on LinkedIn.
 
Position Summary:
Reporting to the Upstream Process Development Lead, the Associate Scientist/Senior Associate Scientist will be responsible for the development of upstream production processes and the production of material for routine in-house development use. This includes all assays associated with cell culture production. The incumbent will also participate in the transfer of the upstream process to support biopharmaceutical product development at Contract Manufacturing Organizations (CMOs). The Associate Scientist/Senior Associate Scientist will interact with the in-house team and the CRO/CMO to ensure timely progress in technology development, documentation, and manufacturing readiness.
Responsibilities include but are not limited to:
Process development:
<ul>
<li>Design, coordinate, and execute process development studies on seed train, bioreactor production, as well as primary recovery, utilizing multiple approaches including statistically designed experiments (DoE). </li>
<li>Design and coordinate scale-down process verification studies.</li>
<li>Design and support process optimization studies.</li>
<li>Coordinate and carry out in-house production of representative materials for development use.</li>
<li>Develop the companys pipeline by supporting process development of new target indications.</li>
<li>Document studies/lab work in lab notebooks, study plans and reports per company requirements to ensure data integrity and traceability. </li>
<li>Stay compliant with lab safety regulations and build good lab practice in everyday lab operations.</li>
</ul>
 Technology Development and Continuous Improvement:
<ul>
<li>Apply and verify novel manufacturing technologies to Auras unique product.</li>
<li>Improve process performance and quality of product.</li>
<li>Contribute to continuous improvement of the internal data management system.</li>
</ul>
 Tech Transfer and PPQ:
<ul>
<li>Support implementation of new process technologies or significant changes to processes, equipment, or manufacturing instructions as needed. </li>
<li>Support tech transfer tasks and support PPQ-enabling activities such as process risk assessment, process characterization and process control strategy development.</li>
<li>Support evaluation of scale up performance and recommend action items to improve scalability, in collaboration with a cross-functional team.</li>
</ul>
 Manufacturing Support:
<ul>
<li>Generate and implement continuous improvement ideas to improve documentation and business practices. </li>
<li>Support manufacturing by providing technical expertise in the manufacturing area and providing timely support for manufacturing investigations using experiments in Process Development.</li>
<li>Other projects as assigned by management.</li>
</ul>
 Minimum Requirements:
<ul>
<li>Degree in biochemical engineering, biological sciences, biochemistry or related discipline. </li>
<li>B.S. with 2-4 (or M.S. with 0-2) years of experience in pharmaceutical, biologics, viral production, or a related field.</li>
<li>Understanding of biologics manufacturing is required in multiple areas. Knowledge and hands-on experience including cell culture development using bioreactors and conducting transfections at varying scales</li>
<li>Ability to critically analyze data using statistical tools and to compile technical reports. </li>
<li>Ability to accomplish projects by deadline in a dynamic environment </li>
<li>Strong oral and written communication skills.</li>
<li>Motivation in performing and learning novel process methods, and good work ethic is critical. Inventory management experience to ensure material supply for upstream process development</li>
</ul>
 Desired Qualifications
<ul>
<li>Experience with DoE using JMP or similar system is highly desired.</li>
<li>Solid understanding of the Quality-by-Design principle and a track record of implementing it in late-stage development (process FMEA, scale-down model qualification and process characterization) is a strong plus. </li>
<li>Virus production experience is strongly desired.</li>
<li>Cell culture experience with Mammalian, Insect, CHO, or Yeast cell lines for biologics production are highly desired.</li>
<li>Experience working with 1L, 10L, and 50L bioreactors is highly desired.</li>
<li>Experience with optimizing process parameters and supplementation to increase product yield and stability (such as transfection parameters) is strongly desired. </li>
<li>Occasional effort may be needed in downstream purification. Any chromatography (AKTA systems) and filtration experience are a plus.</li>
<li>Experience with various analytical procedures is a plus (SDS-PAGE, western blot, ELISA, HPLC, etc.)</li>
<li>An understanding of current good manufacturing practices (cGMPs) as they apply to the development and qualification of biological manufacturing processes.</li>
<li>Proficient in Excel, PowerPoint, and Word applications.</li>
</ul>
 
Salary &amp; Benefit Information:
 
Salary Range: $60,000/yr - $115,000/yr
(Placement within the listed range depends on many factors including, but not limited to: geographic location, degree, years of experience, and internal company equity)
Health insurance with FULL premium coverage
401K with company match
Employee Stock Purchase Program (ESPP)
Competitive paid time off (PTO)
Company-paid short &amp; long-term disability insurance and life insurance

(Sr) Associate Scientist, Upstream Process Development

<h3>Job Description</h3>
Job Description
Welcome to Veradigm, where our Mission is transforming health, insightfully. Join the Veradigm team and help solve many of today's healthcare challenges being addressed by biopharma, health plans, healthcare providers, health technology partners, and the patients they serve. At Veradigm, our primary focus is on harnessing the power of research, analytics, and artificial intelligence (AI) to develop scalable data-driven solutions that bring significant value to all healthcare stakeholders. Together, we can transform healthcare and enable smarter care for millions of people.
Veradigm Life Science
The Veradigm Network is well-positioned to address the unique needs of Life Sciences customers. By leveraging the Veradigm Network, research data and associated insights become both an output of care delivery, as well as additional knowledge to improve quality of care, a true virtuous cycle.
Our portfolio of solutions provides insights using real-world data directly sourced from the Veradigm Network. These solutions can help Life Sciences customers discover timely, actionable real-world evidence to improve patient experience and outcomes, and demonstrate how their products can benefit appropriate patient populations.
Job Summary
Veradigm Life Sciences is currently looking for an experienced Senior Researcher to complement its growing team of healthcare analysts, data scientists and researchers to collaborate on healthcare database analyses and dissemination. The Senior Researcher is tasked with developing and executing complex study designs utilizing real world data (RWD), with end-to-end responsibility from study proposal to publication and presentation. The Senior Researcher will partner with life science clients to anticipate their research needs and foster collaborative research relationships. A background with experience in healthcare data analytics is required, with preference given to epidemiology or pharmacovigilance.***This is a remote based role***
What you will contribute:
<ul>
<li>Develop study proposals and budgets for prospective and retrospective real-world evidence (RWE) studies using a range of real-world data (RWD) assets and approaches.</li>
<li>Design and oversee implementation and conduct of RWE generation conducted by interdisciplinary teams of technical specialists.</li>
<li>Build and maintain relationships with life sciences clients to identify and anticipate their research needs, both in terms of strategy and publication plans.</li>
<li>Communicating complex ideas, methodologies, and results to clients and other stakeholders.</li>
<li>Oversee the delivery of full-scale projects, including:
<ul>
<li>Development of study proposals, working with internal and external stakeholders to scope and plan project work</li>
<li>Identifying and/or applying appropriate statistical techniques</li>
<li>Identifying and interpreting meaningful insights from analysis</li>
</ul>
</li>
<li>Prepare and review abstracts, presentations, and manuscripts and present study findings at scientific meetings.</li>
<li>Maintain project performance in terms of revenue, timeline and resource budget.</li>
</ul>
The ideal candidate will have:
Advanced degree (PhD) in healthcare analytics field of study (epidemiology, health services research, public health, health economics or other quantitative discipline).
Experience:
<ul>
<li>A successful applicant should have 8+ years of experience in a life sciences research consulting space (RWE, HEOR, epidemiology, safety).</li>
<li>Strong client facing skills with the ability to build and maintain relationships, communicate complex ideas, methodologies and results to clients and other stakeholders.</li>
<li>The applicant can demonstrate an ability to simultaneously work across multiple priorities for various stakeholders, including executing and overseeing multiple work products in parallel.</li>
<li>Applicants should be ready to work in a collaborative environment, and they should have a great attitude (e.g., team-focused, loves to get things done).</li>
</ul>
Travel Requirements:
<ul>
<li>No regular travel is required. Occasional travel to educational conferences or presentations, as needed.</li>
</ul>
Working Arrangements:
<ul>
<li>Work can be performed in a standard office environment or in a home office setting.</li>
</ul>
Compliance Job responsibilities include fostering the Company's compliance with all applicable laws and regulations, adherence to the Code of Conduct and Compliance Program requirements, policies and procedures. Compliance is everyone's responsibility.
Enhancing Lives and Building Careers
Veradigm believes in empowering our associates with the tools and flexibility to bring the best version of themselves to work and to further their professional development. Together, we are In the Network. Interested in learning more?
Take a look at our Culture, Benefits, Early Talent Program, and Additional Openings. We strongly advocate that our associates receive all CDC recommended vaccinations in prevention of COVID-19.
Visa Sponsorship is not offered for this position.
At Veradigm, our greatest strength comes from bringing together talented people with diverse perspectives to support the needs of healthcare providers, life science companies, health plans, and the patients they serve. The Veradigm Network is a dynamic, open community of solutions, external partners, and cutting-edge artificial intelligence technologies that provide advanced insights, technology, and data-driven solutions. Veradigm offers a comprehensive compensation and benefits package, including holidays, vacation, medical, dental, and vision insurance, company paid life insurance and retirement savings.
Veradigm's policy is to provide equal employment opportunity and affirmative action in all of its employment practices without regard to race, color, religion, sex, national origin, ancestry, marital status, protected veteran status, age, individuals with disabilities, sexual orientation or gender identity or expression or any other legally protected category. Applicants for North American based positions with Veradigm must be legally authorized to work in the United States or Canada. Verification of employment eligibility will be required as a condition of hire. Veradigm is proud to be an equal opportunity workplace dedicated to pursuing and hiring a diverse and inclusive workforce.
From a "VEVRAA Federal Contractor" We request Priority Referral of Protected Veterans
This is an official Veradigm Job posting. To avoid identity theft, please only consider applying to jobs posted on our official corporate site.
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Life Sciences Senior Researcher - Real World Evidence Team - Remote

<h3>Job Description</h3>
Job DescriptionJob title: Cellular Scientist Location: Andover, MA Duration:18 Months+ Pay range: $51.05/hr. on W2 Position summary: Candidate will be responsible for activities supporting cell-based workflows for a team of researchers, as follows: • Key duties include performing cellular bioanalytical assays in strong adherence with existing protocols and participating in assay optimization efforts; collaborative work with colleagues; accurate documenting all activities in the electronic lab notebook (ELN). This role requires expertise in conducting assays with cells and samples from various tissue origins and experience with ligand binding assays. Knowledge of flow-cytometry is a plus. Position responsibilities: • Cultivation and manipulation of various adherent and non-adherent cell types • Performing ligand binding assays, such as ELISA • Operation of flow-cytometers and plate-readers • Handling tissue samples from rodents, non-human primates and humans • Consistent record keeping using an electronic lab notebook (ELN) Organizational relationships: • This hire will interact daily with the managers and 3-4 colleagues in the immediate team for laboratory work prioritization, experiment planning and exection. The hire might also work on common assignments with colleagues in a larger bioanalytical group at the same location as needed. The hire will participate in bi-weekly group meetings and other team meetings and discussions, as relevant to their work. Education and experience: • B.S. (&gt;4 years), M.S. (&gt;1 years) or Ph.D. in relevant scientific field with a focus on documented experience in performing cell-based assays Educational background in life sciences [cell biology, bioengineering, immunology, or similar] Technical skills requirements: • Required critical skills:
<ul>
<li>Ability to perform cell-based assay by following established protocols and with consistency</li>
<li>Expertise in working with various cell lines and primary cells, especially PBMCs and endothelial cells; sub-culturing and preparation of frozen stocks</li>
<li>Experience with ELISA and/or other ligand binding assays (e.g., MSD)</li>
<li>Being comfortable with task changes and multi-tasking</li>
</ul>
 Preferred:
<ul>
<li>Good working knowledge of cell analysis by flow-cytometry</li>
<li>Primary cell isolation from tissues</li>
<li>Ability for independent data analysis and interpretation</li>
</ul>
 Physical position requirements:
<ul>
<li>Walking, taking the stairs, standing, sitting</li>
<li>Onsite schedule: Monday Friday / 8-4 or 9-5</li>
<li>Interviews: First round: Teams Meeting with HM. Second round onsite with panel.</li>
</ul>
 #sczr2

Cellular Scientist

<h3>Job Description</h3>
Job Description
Job Qualifications:
<ul>
<li>
BS/MS degree in Biology, Biochemistry, Immunology, Bioengineering/Biomedical engineering, or Medical/Pharmaceutical sciences.
</li>
<li>
BS with 3-5+ years' experience; MS with 1-3 years' experience
</li>
<li>
Impeccable lab practices, including aseptic cell line/primary cell maintenance and stimulation.
</li>
<li>
Self-motivated with excellent attention to detail.
</li>
<li>
Demonstrated ability to optimize cell culture conditions, phenotypical assays, Western Blot, migration/contraction assays (fibroblasts), viability assays, qPCR, ELISA/multiplex protein assays, and flow cytometry.
</li>
<li>
Experience with human cell types relevant to tissue homeostasis such as fibroblast, epithelial cells, and macrophages.
</li>
<li>
Familiar with complex in vitro models such as co-culture, tissue explants, Transwells, organoids, 3D/microfluidic/chip systems a plus.
</li>
<li>
Ability to analyze, plot, interpret, and present data in team meetings.
</li>
<li>
Aptitude to communicate in a virtual environment and a hybrid office/virtual setting
</li>
<li>
Proficient at maintaining accurate and well-organized records and laboratory electronic notebooks.
</li>
<li>
5 + years hands-on academia/industry experience
</li>
<li>
Skills:
<ul>
<li>
Primary cell culture and stimulation
</li>
<li>
Molecular biology techniques (e.g. ELISA, qPCR, RNAseq, Western Blot, flow cytometry)
</li>
<li>
Pharmacological treatment with small/large molecules and siRNAs
</li>
<li>
Data analysis including statistics
</li>
</ul>
</li>
</ul>
Benefits:
Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics. 
Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. 
Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.
Technical Certification Bonus: Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.
Synectics is an equal opportunity employer.

Biologist

<h3>Job Description</h3>
About Outlier
Outlier is the worlds leading expert platform, connecting a network of over 100,000 contributors worldwide to improve AI models by providing expert human feedback. We partner with companies including OpenAI, Meta and Microsoft to enable advanced generative AI models to provide accurate responses and advanced reasoning capabilities.
 
We are looking for advanced Chemistry experts to teach AI how to interpret and solve complex problems by:
<ul>
<li>Evaluate AI-generated content for factual accuracy and relevance in Chemistry.</li>
<li>Develop and answer Chemistry-related questions to refine AI understanding.</li>
<li>Assess and rank AI responses based on scientific rigor.</li>
</ul>
Required expertise and qualifications:
<ul>
<li>Education: Masters degree or higher (PhD preferred) in Chemistry or a related field (can be currently enrolled)</li>
<li>Research Experience: Strong preference for candidates with peer-reviewed publications, patents, conference presentations, research grants, or industry R&amp;D contributions</li>
<li>English Proficiency: Ability to read and write with minimal errors</li>
<li>Bonus Skills: AI model training experience is not required but helpful</li>
</ul>

Payment:
<ul>
<li>Currently, pay rates for core project work by Chemistry&nbsp;experts range from $30 to $50 per hour USD but varies based on your geographic location (see note below)</li>
<li>Opportunities for higher-paying research projects based on performance.</li>
</ul>

Rates vary based on expertise, skills assessment, location, project need, and other factors. For example, higher rates may be offered to PhDs. For non-core work, such as during initial project onboarding or project overtime phases, lower rates may apply. Certain projects offer incentive payments. Please review the payment terms for each project.&nbsp;

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