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<h3>Job Description</h3>
Job DescriptionOur MissionOur mission is to solve the most important and fundamental challenges in AI and Robotics to enable future generations of intelligent machines that will help us all live better lives. We aim to advance athletic intelligence to new heights by leveraging simulation-based methods like Reinforcement Learning, augmenting them with model information. Reinforcement Learning Research Scientists will have proven hands-on research or industry experience focusing on one or more of these key areas: Learning-based locomotion, loco-manipulation, or ultra-mobile systems. Having practical hardware experience is essential for this role. If you are passionate about developing technology for robots and using it to advance their capabilities and usefulness, this team will be a great fit for you! This is a senior role. We are looking for experienced industry candidates. Ideally, looking for candidates who have experience working with Humanoids, Legged Robots, Quadrupedal, Locomotion and RL technology.Requirements
<ul>
<li>MS / PhD or equivalent industry experience in robotics, computer science, or related fields</li>
<li>Minimum of 2 years exp. 6+ years of experience in research and development</li>
<li>Ability to demonstrate technical proficiency in Reinforcement Learning, Control, Robotics, or Imitation Learning</li>
<li>Experience with sim-to-real for robotic hardware specifically legged robots or highly dynamic mobile vehicles.</li>
<li>Experience in working with perception-based control</li>
<li>Advanced programming skills in Python or C++</li>
<li>Expertise with deep learning frameworks such as PyTorch and robotic simulation</li>
<li>Proven track record in top-tier conferences and journals in Machine Learning, Robotics, Control, or related fields</li>
</ul>
Bonus
<ul>
<li>Knowledge of Model Predictive Control</li>
<li>Experience in combining model-based and data-driven approaches</li>
<li>Experience in working with Isaac-Gym, Isaac-Sim, or Orbit</li>
<li>Experience in working with ROS or ROS2</li>
<li>Experience with Docker, cloud computing, or similar applications</li>
<li>Experience with parallel programming (e.g., CUDA)</li>
</ul>
&nbsp;These attributes are great to have but not required. Candidates who lack these should not be discouraged from applying. The current reasonable and good faith estimate of the annual base salary range for this position is $128,100 - $237,900, which is based on a number of factors including, but not limited to, relevant skills and experience, educational background and certifications, performance and qualifications, market demand for the role, geographic location, and other organizational needs. An individual candidate may be considered for this position at a different job level, in which case the appropriate salary range will be provided to the candidate after their qualifications have been established. &nbsp;Employees who are new to the RAI Institute typically receive an offer that is between the minimum and the midpoint of the posted salary range to allow for growth within the range over time.&nbsp; &nbsp;Base pay is part of a competitive total compensation package that may include an annual bonus, a long-term cash incentive, monthly cell phone cost reimbursement, commuter cost subsidy, medical benefits, and more. &nbsp;Any final job offer will be determined based on our established compensation range for the role, the candidate’s experience and qualifications, internal parity, and market and business considerations. The advertised pay range is not a guarantee or promise of a specific wage.We provide equal employment opportunities to all employees and applicants for employment and prohibit discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

Research Scientist - Reinforcement Learning

<h3>Job Description</h3>
Job DescriptionOur MissionOur mission is to solve the most important and fundamental challenges in AI and Robotics to enable future generations of intelligent machines that will help us all live better lives. Research Scientists will have proven hands-on research experience with a focus in one or more of these key areas: Cognitive AI, Athletic AI, Organic Hardware Design or Robot Ethics.&nbsp; If you have a passion for developing technology for robots and use it to advance their capabilities and usefulness, you will want to join us!&nbsp;&nbsp; Responsibilities
<ul>
<li>Research focused on advancing robotic systems by developing exciting new ideas and providing solutions to complex problems</li>
<li>Collaborate on publications to be submitted at worldwide conferences</li>
<li>Apply yours and others’ research to real world problems</li>
<li>System Design using model based and data driven techniques</li>
<li>Creatively apply modern learning algorithms to real-world problems</li>
<li>Use your strong development skills to develop algorithms and improve systems</li>
<li>Working with fellow researchers and engineers to develop prototypes</li>
</ul>
Requirements
<ul>
<li>BS, MS or PhD in a robotics-relevant field</li>
<li>5+ years of experience in research and development</li>
<li>Good grasp of a broad set of techniques related to state and world estimation, active control of dynamic systems and planning/cognitive challenges of these types of systems</li>
<li>Strong development skills with at least one programming language</li>
<li>Experience with systems that have complex physical interaction (locomotion &amp; grasping)</li>
</ul>
Bonus
<ul>
<li>Proven track record of publications in top-tier conferences and journals in Machine Learning, Robotics, or related fields (e.g. CVPR, ICCV, ECCV, TPAMI, IJCV, NIPS, ICLR, ICML, IJRR, RSS, etc.) </li>
</ul>
 The current reasonable and good faith estimate of the annual base salary range for this position is $128,100 - $237,900, which is based on a number of factors including, but not limited to, relevant skills and experience, educational background and certifications, performance and qualifications, market demand for the role, geographic location, and other organizational needs. An individual candidate may be considered for this position at a different job level, in which case the appropriate salary range will be provided to the candidate after their qualifications have been established. &nbsp;Employees who are new to the RAI Institute typically receive an offer that is between the minimum and the midpoint of the posted salary range to allow for growth within the range over time.&nbsp; &nbsp;Base pay is part of a competitive total compensation package that may include an annual bonus, a long-term cash incentive, monthly cell phone cost reimbursement, commuter cost subsidy, medical benefits, and more. &nbsp;Any final job offer will be determined based on our established compensation range for the role, the candidate’s experience and qualifications, internal parity, and market and business considerations. The advertised pay range is not a guarantee or promise of a specific wage.We provide equal employment opportunities to all employees and applicants for employment and prohibit discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

Research Scientist

<h3>Job Description</h3>
Job DescriptionAbout Phoenix Tailings&nbsp;Phoenix Tailings is a rapidly-growing clean mining and metals production startup dedicated to sustainable and economic critical metals production. Our mission is to be the world's first fully clean mining and metals production company, producing the resources needed for the next generation of our economy.&nbsp;&nbsp; Why Phoenix Tailings&nbsp;At Phoenix Tailings, we believe that nothing great is ever accomplished alone or without the passion of people who push and motivate one another. If you are someone who shares our relentless pursuit of a better future, passion for innovation, and are excited about working with some of the top innovators in the world, then this is the place for you.&nbsp;&nbsp; Our Values:&nbsp;&nbsp;● You are only crazy if you are wrong, it’s ok to be wrong● Lead with Compassion● Be Resourceful● Listen● Hustle Who We Are Looking For:&nbsp;Phoenix Tailings is seeking a Senior Chemical Engineer to take a leading role in scaling our cutting-edge critical metals recovery processes from lab bench to pilot plant and beyond. You will own the application of mass and energy balances, help design process flows, and ensure the seamless transition of chemistry into scalable, efficient systems. Your work will directly accelerate our ability to produce essential materials cleanly, safely, and economically—pushing the boundaries of what’s possible in sustainable chemical engineering.&nbsp;Key Responsibilities
<ul>
<li>Translate lab-scale chemical processes into scalable unit operations&nbsp;&nbsp;</li>
<li>Design and develop process flowsheets for pilot systems across hydrometallurgical and metallurgical operations.&nbsp;</li>
<li>Lead scale-up efforts for new processes, including equipment specification, system integration, and risk analysis.&nbsp;</li>
<li>Analyze and optimize process performance to improve recovery rates, efficiency, and sustainability metrics.&nbsp;</li>
<li>Work closely with R&amp;D, mechanical engineering, and production teams to ensure seamless handoff from lab to pilot and pilot to production.&nbsp;</li>
<li>Identify bottlenecks and troubleshoot technical challenges in early-stage systems.&nbsp;</li>
<li>Support data collection and process modeling to guide decision-making and future system design.&nbsp;</li>
<li>Drive continuous improvement in process safety, environmental impact, and overall performance.&nbsp;</li>
</ul>
Qualifications:
<ul>
<li>BS, M.S., or Ph.D. in Chemical Engineering or related discipline.&nbsp;</li>
<li>5+ years of experience in chemical process development and scale-up.&nbsp;</li>
<li>Proven experience applying mass and energy balances to develop and optimize process flows.&nbsp;</li>
<li>Background in hydrometallurgy, separations, chemical recovery, or related high-complexity systems.&nbsp;</li>
<li>Familiarity with chemical simulation/modeling tools (e.g., HSC Chemistry, Aspen Plus, MATLAB).&nbsp;</li>
<li>Strong experimental design and data analysis skills.&nbsp;</li>
<li>Track record of delivering chemical processes from lab concept to pilot or production scale.&nbsp;</li>
<li>Passion for clean technology, resource sustainability, and building systems from the ground up.&nbsp;</li>
</ul>
We offer a competitive compensation package that is based on expertise. We also offer the following benefits:
<ul>
<li>Healthcare, we care about you and your family:&nbsp;100% Medical, dental, and vision coverage&nbsp;</li>
<li>Stock:&nbsp;Ownership in a fast-growing venture-backed company.&nbsp;</li>
<li>Family Focus:&nbsp;Parental leave and flexibility for families.&nbsp;</li>
<li>Time Off:&nbsp;Flexible vacation policy to encourage people to get out and see the world.&nbsp;</li>
<li>Team Fun:&nbsp;Regularly scheduled events, and celebrations.&nbsp;</li>
<li>Learning:&nbsp;Learning and development Opportunities to grow your skills and career.&nbsp;</li>
<li>Great team:&nbsp;Working with fun, hard-working, kind people committed to making a difference!&nbsp;</li>
<li>Flexible culture:&nbsp;We are results-focused. We don’t work at the office every day.&nbsp;</li>
</ul>
At Phoenix Tailings, we have an open culture that values learning, and we are looking to grow the team with enthusiastic individuals who share our vision of sustainable mining.&nbsp;&nbsp;&nbsp;Phoenix Tailings, Inc. is an Equal Opportunity Employer, and we value diversity at all levels. All qualified candidates will receive consideration for employment without regard to race, color, religion, sex (including gender identity, sexual orientation, and pregnancy), national origin, age, disability or genetic information, or any other applicable protected characteristics, and these characteristics will not be a factor for consideration of any work-related decisions (including but not limited to hiring, firing, compensation, and discipline).&nbsp;
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

2.2. Senior Chemical Engineer

<h3>Job Description</h3>
Job DescriptionAbout Phoenix Tailings:Phoenix Tailings is a rapidly growing clean mining and metals production startup dedicated to sustainable and economic critical metals production. Our mission is to be the world's first fully clean mining and metals production company, producing the resources needed for the next generation of our economy. We are seeking a Junior Chemical Engineer to join our dynamic team and contribute to the design, development, and optimization of innovative critical metals production systems. Why Phoenix Tailings:At Phoenix, we believe that nothing great is ever accomplished alone or without the passion of people who push and motivate one another. If you are someone who shares our relentless pursuit of a better future, passion for innovation, and are excited about working with some of the top innovators in the world, then this is the place for you. Our Values:● You are only crazy if you are wrong, it’s ok to be wrong● Lead with Compassion● Be Resourceful● Listen● Hustle Who We Are Looking For:Phoenix Tailings is looking for a Development Engineer I with a strong technical foundation and a desire to apply their knowledge to solving real-world process challenges in critical metals recovery. In this role, you’ll support the design, execution, and analysis of rare earth element processing technologies and contribute to building out the technical infrastructure that enables the future of clean manufacturing. This position is ideal for someone with early-career experience or a strong academic background in chemical process engineering, including working with mass and energy balances, PFDs, and P&amp;IDs.&nbsp;Key Responsibilities:
<ul>
<li>B.S. in Chemical Engineering, Metallurgical Engineering, Materials Science, or a related field&nbsp;</li>
<li>1–3 years of experience in chemical or metallurgical process development (internships and co-op experience welcome)&nbsp;</li>
<li>Familiarity with mass and energy balances, process modeling, and basic process calculations&nbsp;</li>
<li>Experience interpreting or developing PFDs and P&amp;IDs&nbsp;</li>
<li>Hands-on experience with laboratory or pilot-scale chemical equipment&nbsp;</li>
<li>Comfortable using tools for data analysis and reporting (Excel, Python, or similar)&nbsp;</li>
<li>Solid communication skills and ability to clearly document technical work&nbsp;</li>
<li>Familiarity with rare earth chemistry or hydrometallurgy is a plus&nbsp;</li>
<li>Driven by curiosity, mission, and a desire to help solve one of the most important resource challenges of our time&nbsp;</li>
</ul>
Qualifications:
<ul>
<li>B.S. or M.S. in Chemical Engineering, Metallurgical Engineering, Materials Science, or a related discipline&nbsp;</li>
<li>3–6 years of hands-on experience in process development, hydrometallurgy, or chemical processing&nbsp;</li>
<li>Proficiency in designing experiments and interpreting data to solve complex technical challenges&nbsp;</li>
<li>Demonstrated expertise in solid-liquid separation, precipitation, and chemical extraction techniques&nbsp;</li>
<li>Strong foundation in process engineering including mass and energy balance modeling&nbsp;</li>
<li>Experience with laboratory instrumentation and analytical tools (e.g., ICP-OES, XRD, SEM)&nbsp;</li>
<li>Clear, structured technical writing skills for documentation and reporting&nbsp;</li>
<li>Comfortable working in a fast-paced, iterative R&amp;D environment&nbsp;</li>
<li>Familiarity with rare earth chemistry and metallurgical challenges preferred&nbsp;</li>
<li>Experience with process simulation tools (e.g., HSC Chemistry, Aspen Plus) is a plus&nbsp;</li>
</ul>
We offer a competitive compensation package that is based on expertise. We also offer the following benefits:
<ul>
<li>Healthcare, we care about you and your family:&nbsp;100% Medical, dental, and vision coverage&nbsp;</li>
<li>Stock:&nbsp;Ownership in a fast-growing venture-backed company.&nbsp;</li>
<li>Family Focus:&nbsp;Parental leave and flexibility for families.&nbsp;</li>
<li>Time Off:&nbsp;Flexible vacation policy to encourage people to get out and see the world.&nbsp;</li>
<li>Team Fun:&nbsp;Regularly scheduled events, and celebrations.&nbsp;</li>
<li>Learning:&nbsp;Learning and development Opportunities to grow your skills and career.&nbsp;</li>
<li>Great team:&nbsp;Working with fun, hard-working, kind people committed to making a difference!&nbsp;</li>
<li>Flexible culture:&nbsp;We are results-focused. We don’t work at the office every day.&nbsp;</li>
</ul>
We offer a competitive compensation package based on expertise, including healthcare coverage (100% medical, dental, and vision), stock ownership, parental leave, flexible vacation policy, learning and development opportunities, and a great team culture that values making a difference and encourages results-focused work. At Phoenix Tailings, we have an open culture that values learning and growth, and we are looking for enthusiastic individuals who share our vision of sustainable mining. Phoenix Tailings, Inc. is an Equal Opportunity Employer, and we value diversity at all levels. All qualified candidates will receive consideration for employment without regard to race, color, religion, sex (including gender identity, sexual orientation, and pregnancy), national origin, age, disability, genetic information, or any other applicable protected characteristics. These characteristics will not be a factor for consideration of any work-related decisions, including but not limited to hiring, firing, compensation, and discipline.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

2.5. Chemical Development Engineer I

<h3>Job Description</h3>
Job DescriptionParallel Squared Technology Institute&nbsp;(PTI) is a non-profit research institute aiming to catalyze a leap in protein analysis technology and use it to explore new biological frontiers. PTI supports open research and educational opportunities supporting rapid career development for scientists, engineers, and mathematicians. Why?&nbsp;Protein dysfunctions directly cause many diseases, such as Alzheimer’s disease. Yet, proteins remain understudied because of technological hurdles. How?&nbsp;To resolve these limitations, PTI will develop mass tags enabling a new&nbsp;framework&nbsp;for multiplexed protein analysis by mass spectrometry towards achieving 100-fold increase in throughput. Scientists at and collaborating with the institute will use these gains to directly investigate disease mechanisms and resolve problems that have proven intractable for decades. Our proof of principle technology and strategies are outlined at:&nbsp;parallelsq.org. New career opportunitiesMembers of PTI will be supported with industry-level resources to lead research projects and disseminate their discoveries and innovations to the broader biomedical community through frequent publications, presentations, and submissions to public data portals.&nbsp;&nbsp; Summary of PositionWe are looking for an individual contributor with previous experience in ‘omics data interpretation,&nbsp; who will lead the design and development of new computational analysis pipelines. This position will involve analyses of mass spectrometry proteomics data in order to infer biological mechanisms at play in either the Alzheimer’s Disease or Immuno-Proteome Aging projects at PTI. The successful candidate will work in a highly interdisciplinary team environment with other scientists. In order to be seriously considered for this position, we require a cover letter as part of the candidate’s application.Responsibilities:
<ul>
<li>Develop and adapt pre-processing algorithms for mitigation of data collection artifacts</li>
<li>Work with biological project leads to define hypotheses and apply appropriate statistical framework</li>
<li>Design and develop optimized analysis pipelines for large ‘omics datasets</li>
<li>Perform deep and detailed analyses for data-intensive experiments with team members and communicate interpretable results</li>
<li>Hands-on development of interactive tools for data interpretation of high throughput proteomics datasets for other team members using RShiny, Python, D3, or other tools</li>
<li>Curate large-scale datasets for internal and external usage</li>
<li>Mentor scientists and research associates</li>
<li>Prepare internal reports and manuscripts as well as present results at internal or external scientific meetings as appropriate</li>
<li>Demonstrate a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others</li>
<li>Other duties as assigned</li>
</ul>
Qualifications:
<ul>
<li>Advanced degree in Statistics, Mathematics, Bioengineering, Computer Science, or other computational science.&nbsp;</li>
<li>Demonstrable professional or PhD experience working with professional biologists on single cell ‘omics questions</li>
<li>Strong understanding of generalized linear models and nonparametric regression, hypothesis testing, optimization, dimension reduction techniques, and machine learning algorithms</li>
<li>Advanced proficiency in R and/or Python</li>
<li>Demonstrable experience with data set alignment, batch correction, cell type assignment, differential abundance testing, and gene ontology mapping</li>
<li>Experience handling terabyte-scale biological data</li>
<li>Demonstrable experience with model validation: cross validation, bootstrapping, posterior predictive, or simulation-based model checking</li>
</ul>
Preferred Qualifications:
<ul>
<li>Experience with proteomics spectral library prediction</li>
<li>Must have single cell 'omics experience OR experience working with mass spectrometry data</li>
</ul>
We offer:
<ul>
<li>An opportunity to change the world and work with some of the smartest and the most talented experts from different fields.</li>
<li>Excellent medical, dental, and vision insurance with many $0 premium options for you and your family with several national and regional providers. Most employees have more than 20 plan options to choose from.</li>
<li>Company-paid group life, AD&amp;D, long- and short-term disability insurance</li>
<li>15 days PTO + 10 sick days per year</li>
<li>18 company holidays + your birthday off</li>
<li>$5,000 per year educational reimbursement</li>
<li>Up to 16 weeks paid parental leave</li>
</ul>
We aim to help fill a structural gap in today's R&amp;D system. We enable fundamental research that requires unusual levels of scale and coordination yet is not rapidly monetizable by industry. We’re bringing together top talent from academia, industry, and startups to build a new model for innovative R&amp;D. As an incubator within the Schmidt Futures Network, we identify high-impact scientific or technical research and development opportunities, ultimately defining and launching these projects as Focused Research Organizations.&nbsp;We are an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by applicable local, state, or federal law or company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

Computational Scientist - Single-Cell Algorithms

<h3>Job Description</h3>
Job DescriptionCrossbow Therapeutics is seeking a highly motivated and detail-oriented Associate Scientist - Protein Sciences to join our Antibody Development Team in Cambridge, MA. This individual will contribute to the development and characterization of therapeutic antibodies for both therapeutic applications and research initiatives. This role provides the opportunity to work collaboratively with cross-functional teams to produce, purify, and analytically characterize antibodies and fusion proteins. The ideal candidate will possess a solid foundation in biochemistry or a related field, along with hands-on experience in protein analytical techniques, production, and purification. If you are passionate about protein science and eager to make a significant contribution, this role offers a dynamic opportunity to contribute to innovative therapeutic developments.Essential Duties and Responsibilities:
<ul>
<li>Design, develop, and implement sophisticated analytical methods (HPLC, BLI, ELISA, etc.) for the characterization of antibodies and other proteins.</li>
<li>Conduct comprehensive analyses to assess protein purity and quality using SDS-PAGE, UV/Vis spectroscopy, HPLC tools, and other relevant analytical methods.</li>
<li>Perform production of recombinant monoclonal and bispecific antibodies, and other proteins using mammalian protein expression systems (e.g., CHO, HEK293).</li>
<li>Implement various chromatography methods (affinity, IEX, SEC, HIC, MMC) for the purification of antibodies and other proteins.</li>
<li>Support characterization of antibodies using cell-based assays (cytotoxicity, cytokine production, and other).</li>
<li>Operate and maintain AKTA FPLC systems and analytical HPLC instruments to ensure efficient workflow.</li>
<li>Address and resolve technical challenges that arise in protein analytical and purification workflows, ensuring high-quality results.</li>
<li>Document and maintain precise records of laboratory activities using an electronic laboratory notebook (Benchling) and communicate findings clearly through written reports and presentations.</li>
<li>Actively stay informed about advancements in protein analytical, production, and purification technologies to continuously enhance methodologies.</li>
<li>Provide technical and resourcing support to other functional groups as needed.</li>
</ul>
Requirements
<ul>
<li>Bachelor's degree + 6 years with relevant experience, Master's + 3 years with relevant experience, or Ph.D. in Biochemistry, Molecular Biology, or a related field.</li>
<li>Strong demonstrated hands-on expertise in mammalian expression systems (CHO and HEK293) is required.</li>
<li>Proven track record in protein and antibody analytical development, with expertise in method development, optimization, and troubleshooting of chromatography-based assays and protein–protein interaction analyses.</li>
<li>Validated technical understanding and applied technical expertise to develop, optimize, and troubleshoot methods key assays across drug development, including HPLC and UPLC instruments</li>
<li>Extensive experience with AKTA instrumentation, in various purification techniques (e.g., affinity, ion exchange, HIC, SEC) as well as protein quality control methods.</li>
<li>This position requires on-site work 5 days per week at our office in Harvard Square, Cambridge, Massachusetts.&nbsp;</li>
</ul>
Additional Knowledge, Skills and Abilities
<ul>
<li>Experience with therapeutic antibody developability assessments is a plus.</li>
<li>Excellent problem-solving skills complemented by keen attention to detail.</li>
<li>Ability to thrive both independently and collaboratively in a fast-paced environment.</li>
<li>Flexibility to adapt to changing plans.</li>
<li>Strong communication and organizational skills to support effective teamwork.</li>
</ul>
The Benefits of Working at Crossbow
<ul>
<li>We offer a competitive compensation that includes an annual discretionary bonus and equity package, allowing you to have a stake in our long-term success. Base salary will be commensurate with experience and in the range of $105,000-$130,000 for an Associate Scientist and $120,000 - $150,000 for a Scientist. </li>
<li>Take care of your physical and mental health through our subsidized medical, dental and vision insurance programs.</li>
<li>Enjoy work and life with our flexible paid time off program, annual holidays including a Winter Break and sick time.</li>
<li>Utilize our tuition reimbursement program to further your education.</li>
<li>Maximize your future retirement by participating in our 401k program.</li>
</ul>
About CrossbowCrossbow Therapeutics, Inc., is a biotechnology company determined to improve the lives of people with cancer by unlocking the therapeutic potential of T-cell receptor (TCR)-mimetic antibodies. The company’s T-Bolt™ therapies are next-generation, easily assembled immunotherapies directed with high precision at previously unreachable cancer cell targets. Crossbow’s efficient and selective approach is designed to target the entire universe of cancer proteins, dramatically expanding the potential of antibody therapy to address many types of cancer. Crossbow Therapeutics is proud to be an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace where every individual is respected and valued. We recognize that diversity fuels innovation and enhances our capacity to achieve meaningful outcomes through our work. Note to Recruiters: Please be aware that we do not accept unsolicited resumes and kindly request that you do not contact our team regarding this job posting. If a resume is submitted to a Crossbow team member without a prior agreement, we will not be obligated to pay any referral or placement fees.

Associate Scientist / Scientist - Protein Sciences

<h3>Job Description</h3>
Job DescriptionParallel Squared Technology Institute&nbsp;(PTI) is a non-profit research institute developing technologies, reagents, and computational tools to increase the sensitivity and throughput of protein analysis, with a specific focus on single-cell proteomics. We are applying these innovations to societally-relevant areas of biomedical research. As part of these efforts, we are developing new approaches to study protein dysfunctions in Alzheimer’s and related neurodegenerative diseases. Summary of PositionWe are seeking scientist and senior scientist candidates to help drive our efforts to use single-cell proteomics to understand the causes of Alzheimer’s and related neurodegenerative diseases.&nbsp; Ideal candidates will have expertise in the molecular mechanisms of neurodegeneration and&nbsp;direct, hand-on&nbsp;experience in single-cell analysis, computational biology, and brain tissue handling.&nbsp; Candidates will have the opportunity to work as part of an interdisciplinary team in multiple areas, including on NIH-funded projects, using proteomic technologies developed at PTI to discover new molecular mechanisms of neurodegeneration in Alzheimer’s and related disorders.&nbsp; Day-to-day responsibilities include designing and carrying out experiments to isolate and profile single cells from brain tissue, computationally analyzing large-scale single-cell proteomics datasets, preparing manuscripts and presentations, mentoring junior scientists, and regular meetings with collaborators in and outside of PTI. Candidates will initially work on ongoing projects but will have the opportunity to design and lead their own projects as well.&nbsp;&nbsp; Candidates with less than 1 year of postdoctoral experience will be considered for the scientist position and those with more than 1 year of experience will be considered for the senior scientist position.&nbsp; About PTIPTI is a nonprofit, focused research organization (FRO) established through Convergent Research.&nbsp; FROs aim to accelerate progress across science and technology by tackling large-scale problems with the potential to unlock existing bottlenecks in specific research areas.&nbsp; PTI aims to achieve a 100-1000x increase in the scale of proteomic analysis.&nbsp; To do so, we are developing new technologies and approaches for mass spectrometric proteomics.&nbsp; This includes molecular barcodes, termed “mass tags” that enable sample multiplexing, as well as computational approaches for increasing the sensitivity of protein analysis.&nbsp; We aim to apply these advances in societally-relevant areas, with a specific focus on neurodegenerative disease.&nbsp; To do so, we are collaborating with leaders in neurodegenerative disease from around the world.&nbsp; To learn more about PTI’s approach for studying neurodegenerative disease, please visit this page.&nbsp; To learn more about our technology for increasing the throughput of protein analysis, please visit here.&nbsp;&nbsp; Researchers at PTI have the opportunity to work within an interdisciplinary team of mass spectrometrists, chemists, computational analysts, and biologists to push the boundaries of protein analysis. PTI supports professional development through educational opportunities such as travel to conferences workshops.&nbsp;&nbsp; Members of PTI receive industry-level resources to lead research projects and have the opportunity to disseminate their discoveries and innovations through high-visibility publications, presentations, and submissions to public data portals.&nbsp;&nbsp;Responsibilities:
<ul>
<li>Design and execute research projects using single-cell proteomics to understand the molecular mechanisms of neurodegeneration in Alzheimer’s and related disease.&nbsp;</li>
<li>Computationally analyze large-scale, single-cell proteomic datasets to identify new molecular mechanisms of disease.</li>
<li>Collaborate with external laboratories, brain banks, and tissue repositories on sample procurement.</li>
<li>Prepare human brain tissue samples for proteomic analysis using methods and technologies developed at PTI.</li>
<li>Help junior scientists gain expertise in experimental techniques used at PTI, analyzing and interpreting experimental results, recording data in laboratory notebooks, and writing up and presenting research results.</li>
<li>Make regular presentations within PTI and to collaborators.</li>
<li>Prepare manuscripts related to project outcomes and grant applications for external funding.</li>
<li>Demonstrate a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others.</li>
<li>Other duties as assigned.</li>
</ul>
Qualifications:
<ul>
<li>PhD Neuroscience or a related field.</li>
<li>Direct, hands-on experience in preparing human brain tissue for downstream analyses.&nbsp;</li>
<li>Direct, hands-on experience with single cell analysis.</li>
<li>Excellent communication and interpersonal skills, record keeping ability, and attention to detail.</li>
</ul>
Preferred Qualifications
<ul>
<li>Experience in high throughput or automated tissue sample collection, preparation, and analysis, particularly with human brains.</li>
<li>Experience with mass spectrometry proteomics.</li>
<li>Fluency in R or Python, particularly in the context of single-cell analysis.</li>
</ul>
We offer:
<ul>
<li>An opportunity to change the world and work with some of the smartest and the most talented experts from different fields.</li>
<li>Excellent medical, dental, and vision insurance with many $0 premium options for you and your family with several national and regional providers. Most employees have more than 20 plan options to choose from.</li>
<li>Company-paid group life, AD&amp;D, long- and short-term disability insurance</li>
<li>15 days PTO + 10 sick days per year</li>
<li>18 company holidays + your birthday off</li>
<li>$5,000 per year educational reimbursement</li>
<li>Up to 16 weeks paid parental leave</li>
</ul>
We aim to help fill a structural gap in today's R&amp;D system. We enable fundamental research that requires unusual levels of scale and coordination yet is not rapidly monetizable by industry. We’re bringing together top talent from academia, industry, and startups to build a new model for innovative R&amp;D. As an incubator within the Schmidt Futures Network, we identify high-impact scientific or technical research and development opportunities, ultimately defining and launching these projects as Focused Research Organizations.&nbsp;We are an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by applicable local, state, or federal law or company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

Neurodegenerative Disease Senior Scientist

<h3>Job Description</h3>
Job DescriptionCompany Profile Founded in 1977, GMO is a global investment manager committed to delivering superior long-term investment performance and advice to our clients. We offer investment strategies and solutions where we believe we are positioned to add the greatest value for our investors. These include multi-asset class, public equity, public credit, and liquid alternative offerings. &nbsp;We manage approximately $68bn for a client base that includes many of the world’s most sophisticated institutions, financial intermediaries, and private clients. Industry-wide, we are well known for our focus on valuation-based investing, willingness to take bold positions when conditions warrant, and candid and academically rigorous thought leadership. Jeremy Grantham, GMO’s Co-Founder and Long-Term Investment Strategist, is renowned as an expert in identifying speculative investment bubbles and also as a leading climate investor and advocate.&nbsp;GMO is privately owned and employs over 430 people worldwide. We are headquartered in Boston, with additional offices in Europe, Asia and Australia. Our company-wide culture emphasizes commitment to clients, intellectual curiosity, and open debate. We celebrate and respect our differences, while embracing and valuing what each of us brings to work, as we know that diverse teams in an inclusive, caring environment achieve higher engagement and better client results. Please follow the prompts included in this job posting to apply. The application window for this role is anticipated to remain open until the job is filled, or as otherwise determined by GMO.&nbsp; Position Description:GMO is seeking a quantitative researcher to join our Systematic Equity Team. The candidate will work closely with researchers and portfolio managers to support the team’s rigorous research agenda. The team’s research process is structured to analyze significant amounts of historic, current, and projected financial characteristics as well as detailed macroeconomic data. This individual will work closely with other members of the team on various research and investment related topics.&nbsp; This will include model-building, data cleaning, portfolio analysis and integration with all available GMO data sources. This position is located in our Boston office with the opportunity to work a hybrid schedule.&nbsp; Responsibilities: •Work closely with team members to develop and to support investment research projects.&nbsp;•Enhance and expand our processes by conducting deep research on targeted projects using state-of-the-art modeling techniques.•Develop creative investment ideas independently and articulate why those ideas fit into our process.•Conduct in-depth financial accounting and capital markets research to support equity investment strategies.•Develop and implement quantitative models using a variety of valuation techniques, such as dividend discount models and free cash-flow models.•Design and implement solutions to make a positive impact on the investment research and analysis environment, and to increase efficiency, depth, breadth, and throughput of quantitative research capabilities.•Enhance both our bottom-up and top-down valuation models used for identifying investment opportunities.•Work closely with colleagues in Technology, Investment Data Solutions and across other investment teams to enhance existing databases and quantitative processes.•Support portfolio managers with ad-hoc research requests.•Provide support for portfolio construction and management activities.•Participate in periodic portfolio rebalancing.•Monitor portfolio positions and risk exposures and work with the execution team on trading strategies and analysis. Required Skills and Characteristics: •The ideal candidate will have 5-8+ years of relevant experience in quantitative investing.•An advanced degree in accounting, Ph.D. preferred.•Strong understanding of financial accounting principles and practices.•Deep knowledge of modern valuation techniques, including dividend discount models and free cash-flow models.•Proficiency in Python for quantitative analysis and model development.•The ideal candidate will have demonstrated the ability to:- Work independently or collaboratively as part of a team, with a strong work ethic and sense of ownership.- Form actionable plans for solutions.- Generate functional, efficient software and documentation.- Work in source control and advance a shared code base.- Effectively manage multiple projects with strong prioritization skills.- Learn technical skills in new domains quickly.- Show a passion for applied research and technology.•This person should have the ability to develop creative investment ideas on their own and clearly articulate the ideas.&nbsp;•Solid written and verbal communication skills are important and the ability to effectively communicate with a wide array of investment and technology professionals is critical. This is a reasonable, good faith estimate of the current salary range for this role. GMO’s salary range accounts for a wide array of factors that are considered in making compensation decisions including but not limited to skill sets and market demand for skills; level of experience and training; specific qualifications, performance, time in role/company, geographic location, and other business and organizational needs. &nbsp;In addition, this position is eligible for a discretionary annual bonus award, which award may be determined by individual, team, department and firm performance, and is subject to the terms of GMO’s compensation plan. This position is also benefits eligible. GMO’s comprehensive benefits program includes medical insurance, dental insurance, life insurance, long-term disability coverage, a 401(k)/profit-sharing retirement plan, open paid time off, leaves of absences, dependent care resources, tuition reimbursement, charitable gifts matching, flexible spending accounts, and commuter benefits.GMO is committed to the recruitment, employment, and promotion of all candidates equally, regardless of an individual's gender, race, color, national origin, ancestry, age, religion, pregnancy, marital status, sexual orientation, gender identity or expression, military or veteran status, genetic information, physical or mental disability (except where such disability is a bona fide occupational disqualification) or any other classification protected under federal, state or local law.

Quantitative Research Analyst

<h3>Job Description</h3>
Job DescriptionSublime is advancing a breakthrough, clean, efficient, low-waste process for manufacturing cement, the essential ingredient in the most-consumed human-made material on Earth: concrete. Replacing 200-year-old manufacturing methods that are reliant on kilns running hotter than lava, our near-ambient-temperature, electrochemical technology manufactures industry-accepted cement and critical minerals. We’re partnering with leading general contractors, concrete producers, developers, and technology hyperscalers to deploy our clean, durable, beautiful Sublime Cement® in infrastructure that is defining the future of clean construction. Backed by some of the world’s largest cement producers, leading private investors, and the U.S. Department of Energy, we are assembling a talented, collaborative team that is "amped about cement" (pun intended) and committed to operating on the frontiers of material science, manufacturing, industry, construction, and commercial partnerships, to advance cement innovation that will endure for the next millennium. &nbsp;Sublime is seeking a Senior Scientist to contribute to the development of our decarbonized cement with special expertise in rheology and milling of cementitious materials. This Scientist will be responsible for managing and conducting research to improve the performance of Sublime Cement through literature reviews, designing experiments, performing hand-on characterization and testing in lab, analyzing and interpreting data, and communicating results. This Scientist will also contribute their expertise to help set technical priorities and research strategy, plan and prioritize experiments, and contribute to the successful operation of our shared laboratory.&nbsp;&nbsp;&nbsp;This is an individual contributor role that will report to Sublime’s Head of Product R&amp;D. This position is in person at Sublime’s headquarters in Somerville, MA, with occasional flexibility to work from home as appropriate based on team and project needs.&nbsp;&nbsp;This is an individual contributor role that will report to Sublime’s Head of Product R&amp;D. This position is in person at Sublime’s headquarters in Somerville, MA, with occasional flexibility to work from home as appropriate based on team and project needs.&nbsp;Responsibilities for this role will include:
<ul>
<li>Developing and implementing new experimental methods and tools to validate and optimize the performance of Sublime’s cement&nbsp;</li>
<li>Managing and keeping track of multiple work streams simultaneously</li>
<li>Working closely with Process R&amp;D teams to establish a tight feedback loop and continue to improve cement performance</li>
<li>Performing lab experiments including rheology, milling and grinding, cement property measurements, analyzing data, and presenting results&nbsp;</li>
<li>Design and execute rheological experiments to characterize the flow behavior of cementitious materials and additive/admixture compatibilities</li>
<li>Evaluate grinding parameters for particle size distribution and surface area of cement to optimize fresh and hardened properties</li>
<li>Devising and implementing strategies to improve cement performance&nbsp;</li>
<li>Prioritizing and organizing the team’s research activities&nbsp;</li>
<li>Contributing to the development of Sublime’s technology through literature reviews and informational interviews with industry experts&nbsp;</li>
<li>Maintain, calibrate, and expand rheological testing capabilities in the lab</li>
<li>Writing white papers, reports, and patent applications&nbsp;</li>
<li>Championing safety, especially in the development of experimental processes</li>
<li>Fostering a supportive, inclusive, innovative, and dynamic company culture</li>
</ul>
Sublime Systems is proud to be an Equal Opportunity EmployerAll qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status, or any other characteristic protected by law. Your Right to WorkIn compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification document form upon hire. Notice of E-VerifySublime Systems use E-Verify to confirm the identity and employment eligibility of all new hires.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

Senior Scientist

<h3>Job Description</h3>
Job DescriptionOur mission is to solve the most important and fundamental challenges in AI and Robotics to enable future generations of intelligent machines that will help us all live better lives. Team Overview:Robots need to make significant progress in manipulation performance and capabilities before they become commonplace in our lives. The Manipulation team is developing robot mechanisms and behaviors that enable smooth, efficient execution of manipulation tasks. Our goal is for robots to operate with human-like cadence and versatility, with enough generalization to perform multiple tasks within the same domain in any appropriate environment. Our Research Spans:Improving hardware for high-speed, high-strength, and dexterous manipulation, including underactuated manipulatorsUsing learning methods to develop robust capabilities for novel environmentsDeveloping parameterized skills and chaining them into long-horizon behaviorsApplying robust strategies for failure recovery in manipulation tasks Role Overview:We seek an Applied Scientist / Research Scientist to advance the state of the art in long-horizon, robust, dexterous manipulation learned from few demonstrations. The role involves researching, developing, and validating new algorithms and models for skill learning, composition, and real-world deployment. You will collaborate across hardware, software, and research teams to integrate and test these capabilities in physical robotic systems.Basic Qualifications:
<ul>
<li>PhD or equivalent experience in robotics, computer science, mechanical engineering, or related field</li>
<li>Master’s degree with several years of industry or applied research experience</li>
<li>Bachelor’s degree with significant and relevant hands-on industry experience</li>
<li>7 Years in Research and Development</li>
<li>Expertise in machine learning for control, imitation learning, and/or reinforcement learning</li>
<li>Experience with robot manipulation, motion planning, and perception systems</li>
<li>Proficiency in Python and C++</li>
</ul>
 Preferred Qualifications:
<ul>
<li>Publications in top-tier robotics or AI venues</li>
<li>Experience deploying algorithms on real robotic platforms</li>
<li>Knowledge of dexterous manipulation, task and motion planning, behavior abstractions, skill completion prediction, failure detection and recovery, and/or using machine learning models for long-horizon skill chaining. </li>
<li>Ability to solve problems rapidly in hands-on, real-world scenarios</li>
</ul>
The current reasonable and good faith estimate of the annual base salary range for this position is $128,100 - $237,900, which is based on a number of factors including, but not limited to, relevant skills and experience, educational background and certifications, performance and qualifications, market demand for the role, geographic location, and other organizational needs. An individual candidate may be considered for this position at a different job level, in which case the appropriate salary range will be provided to the candidate after their qualifications have been established. &nbsp;Employees who are new to the RAI Institute typically receive an offer that is between the minimum and the midpoint of the posted salary range to allow for growth within the range over time.&nbsp; &nbsp;Base pay is part of a competitive total compensation package that may include an annual bonus, a long-term cash incentive, monthly cell phone cost reimbursement, commuter cost subsidy, medical benefits, and more. &nbsp;Any final job offer will be determined based on our established compensation range for the role, the candidate’s experience and qualifications, internal parity, and market and business considerations. The advertised pay range is not a guarantee or promise of a specific wage.We provide equal employment opportunities to all employees and applicants for employment and prohibit discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

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