Job Description
Job Description
Responsibilities:
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We are seeking a highly motivated contractor/Scientist III to join the Tissue Homeostasis team.
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Work with the company's Disease Discovery Teams (DDTs) and Genomics Research Center (GRC) team members to design and execute in vitro cell biology and mechanism of action experiments to advance target validation and assay platform development efforts in using immune cells and stromal cells.
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Perform mammalian cell culture of primary and transformed cells.
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Develop immune-stromal cell co-culture systems (e.g. Myeloid cells-fibroblast) to dissect signal transduction in cell-cell interactions with disease relevant cues
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Perform qPCR analysis, flow cytometry, and Western Blotting analysis.
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Perform cell-based assay with human primary cells and human cell lines (AlphaLISA, ELISA, HTRF, and proliferation assays).
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Utilize technical knowledge and experience to effectively troubleshoot and optimize assays.
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Maintaining laboratory notebooks to the required company standard.
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Communicating results to internal meetings.
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Interpret findings and effectively present scientific data, concepts, and recommendations to various internal audiences.
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Compile and review technical reports, protocols, manuscripts, and other key documents.
Requirements:
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Current or perspective BS/MS/PHD students in Biotechnology, Immunology, Molecular Biology, Cell Biology or Microbiology
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PHD students in Biotechnology, Immunology, Molecular Biology, Cell Biology or Microbiology
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5 + years' experience
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Ability to work in a fast-paced environment and delivery results in a timely and agile manner.
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Ability to work independently and collaboratively with cross-functional teams.
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Willing to learn new techniques and develop new assays as needed
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Extensive cell biology and immunology experience, proficiency in working with human primary cells and immortalized cell lines.
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Experience with co-culture systems or complex in invitro systems with primary human cells esp. T Cells.
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Demonstrated knowledge and experience of key cell biology assays and techniques.
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Genetic manipulation of human cells using shRNA/siRNA/CRISPR tools.
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Proficiency in molecular biology skills such as qPCR analysis, flow cytometry, and Western Blotting analysis.
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Trouble-shooter able to adapt ideas and experiments to achieve key project objectives and adhere to timelines.
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Excellent communication of complex scientific ideas (written and verbal) and interpersonal skills.
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Strong organizational skills required, in particular good time management skills.
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Inclusive, open-minded, collaborative, and forward-thinking.
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Background in cell biology of inflammation or Immunology
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Excellent oral and written communication, analytical, and computer skills.
Benefits:
Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.
Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.
Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.
Technical Certification Bonus: Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.
Synectics is an equal opportunity employer.