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Biologist

Synectics Inc
locationCambridge, MA, USA
PublishedPublished: 6/14/2022
Science
Full Time

Job Description

Job Description

Description:

  • We are currently seeking a highly motivated and passionate scientist to join our team in Immunology Discovery department.

  • The candidate will focus on generating biology data package to help advance target identification and validation within GI immunology.

  • The position offers a unique opportunity for a talented scientist to work in a dynamic, innovative, and multi-disciplinary environment to develop their career at the interface of basic research and early drug discovery.

  • The scientist will focus on developing and optimizing cellular/molecular assays to generate reliable and reproducible data in a timely manner.

  • The scientist is expected to read and adapt scientific literature and internal protocols to accomplish assignments and demonstrate broad and versatile technical expertise within immunology.

  • The position requires ability to work independently, have excellent technical, written and oral communication skills and work very well in a collaborative team environment.

  • Develop cell-based functional assays using cell lines and mammalian tissue primary cells

  • For functional assays, measure readouts including cell activation, differentiation and effector molecule secretion

  • Perform advanced molecular and cellular biology techniques (including but not limited to FACS, ELISA, MSD, HTRF)

  • Isolate and culture immune cells from relevant human and mouse tissues

  • Work with non-immune cells and develop relevant assays to evaluate interactions with immune cells that are relevant to the project

  • Work independently on the design, execution and interpretation of experimental results to validate hypotheses related to the project need

  • Implement and innovate new experimental protocols/techniques as needed

  • Analyze, interpret, document and report data consistently, concisely and rigorously, both to individual stakeholders and in group settings

  • Demonstrate scientific excellence through dedication to multiple projects in a fast-paced multi-disciplinary environment

  • Impact projects mostly through lab-based activities

Qualifications:

  • Bachelor's degree or master's degree in Biological Science or related field with 3-5 years of experience in biotech or pharma set up.

  • Experience in in vitro cell culture (sterile techniques, handling challenging cell types) and cell-based assays development is required.

  • Experience with immune cells including T cells and myeloid cells (monocytes or dendritic cells) is required.

  • Experience in immunoassays including multi-color flow cytometry and ELISA (or MSD, HTRF) is required.

  • Experience with non-immune cells including fibroblasts and epithelial cells is a plus but not required.

  • Knowledge of DNA/RNA handling and other molecular biology techniques like PCR and qPCR is a plus.

  • Ability to learn new skills and apply them in a fast-paced research environment.

  • Creativity, problem-solving, and attention to details.

  • Excellent oral and written communication and collaboration skills.

  • Ability to work independently as well as in a team.

  • Proven flexibility to deal with changing timelines and shifting work priorities.

Benefits:

Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.

Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.

Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.

Technical Certification Bonus: Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.

Synectics is an equal opportunity employer.

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